Principal Investigator

  • Paul Shaw, Ph.D.

    Ph.D. Biopsychology, University of Chicago
    M.A. Psychology, San Jose State University
    B.A. Psychology and Criminal Justice, Niagara University

    I received my Ph.D. working with Al Rechtschaffen at the University of Chicago where I received excellent training in all aspects of animal and human sleep research. I subsequently joined The Neurosciences Institute as a postdoctoral fellow with Giulio Tononi where I led a team that pioneered the use of the fruit fly as a model system to study sleep. As a PI at the Neurosciences Institute, I developed novel strategies to identify molecular mechanisms that are associated with the negative effects of prolonged waking in flies. Upon joining the Department of Anatomy and Neurobiology at Washington University in St. Louis School of Medicine, I developed tools to evaluate the interrelationship between sleep and memory and have begun to extend these findings to conditions of aging associated with disturbed sleep such Alzheimer’s disease. Importantly, these studies have resulted in strategies that are exceptionally well suited for establishing cause-effect relationships between sleep and cognitive abilities during health and disease.

    E-mail: shawp (at) pcg.wustl (dot) edu

  • Staff Scientists

  • Stephane Dissel

    Ph.D. Genetics, University of Leicester
    M.S. Molecular Biochemistry, University of Strasbourg
    B.S. Biology, University of Strasbourg

    I began my career working with Dr. Dominique Ferrandon at the University of Strasbourg in France. During this time I was introduced to fly genetics working alongside Dr. Jules Hoffmann's group. This was an exciting time and led me to pursue doctoral studies in genetics at the University of Leicester working with Drs. Kyriacou and Rosato. We made great strides in elucidating the organization of the clock circuitry underlying circadian rhythms. The ability to dissect circuity underlying behavior piqued my interest in sleep. I began pursuing investigations into sleep at the University of Warwick as an independent investigator. I then had the opportunity to join the Sleep Research lab at Washington University School of Medicine in St. Louis to investigate the relationship between sleep and plasticity.

    E-mail: dissels (at) pcg.wustl (dot) edu

  • Krishna Melnattur

    Ph.D Molecular and Cell Biology, UMASS Amherst
    B.S. Biotechnology, Anna University, Madras, India

    I came to St Louis via Amherst, MA where I did my doctoral dissertation work with Dr. John Nambu at UMass studying wiring of the fly olfactory system, and DC where I did postdoctoral work with Dr Chi-Hon Lee at the NIH defining neural circuits required for fly color vision. When not bemoaning deep dish pizza and provel cheese, or devising strategies to convince Americans of the inherent superiority of a proper sport like cricket, I spend my time genetically dissecting sleep regulatory circuits.

    E-mail: melnatturk (at) pcg.wustl (dot) edu

  • Veena M. Angadi, M.D., M.S.

    M.D. Jawaharlal Nehru Medical College
    M.S. Biotechnology, Illinois State University

    I received my medical degree from Jawaharlal Nehru Medical College, K.L.E University, Karnataka, India and MS in Biotechnology from Illinois State University under the guidance of Dr Kevin A. Edwards where I studied the role of Wnt signalling pathway in fly Oogenesis and cell differentiation. I joined the Shaw lab in Jan 2012 and am currently studying sleep and the molecular mechanisms involved in modulating memory, plasticity and the Immune mediators.

    E-mail: angadiv (at) pcg2.wustl (dot) edu

  • Undergraduate Students

  • Regine Rosas

    Biomedical Engineering, Brown University 2017

    I recently finished my first year studying biomedical engineering at Brown University. I returned to St. Louis for my summer break and joined the Shaw lab. I am unsure of her plans after college, but hope to travel as much as possible. I grew up in Boston and am often ridiculed in the lab for my loyalty to the Red Sox.

    E-mail: regine_rosas (at) brown (dot) edu

  • Lab Technicians

  • Zach Koch

    B.S. Cell and Moelcular Biology, Missouri State University

    I recently graduated from Missouri State University where I received my Bachelor of Science in Cell and Molecular Biology. I am a St. Louis local and am now working on my MPH.

    E-mail: zachary.koch (at) ymail (dot) com

  • Mike Toth

    B.S. Neuroscience, Saint Louis University

    I am a recent graduate of Saint Louis University where I recieved my B.S. in Neuroscience. I am orignally from the Chicago area, and am a big Chicago sports fan. Yes, I am a Cubs fan living in St. Louis. I intend to eventaully matriculate to medical school or go to graduate school to study neuroscience.

    E-mail: tothm (at) pcg.wustl (dot) edu